Antioxidant Activity of Six Marine Sponges Collected from the Persian Gulf Antioxidant activity of marine sponges
Iranian Journal of Pharmaceutical Sciences,
Vol. 8 No. 4 (2012),
1 October 2012
,
Page 249-255
https://doi.org/10.22037/ijps.v8.40926
Abstract
Compounds especially from natural sources are capable of protecting against reactive oxygen species (ROS) mediated damage. Therefore, there is a growing interest in novel substances exhibiting antioxidant properties. Several marine environments can provide a rich source of novel biologically active compounds. The aim of this paper is to evaluate in vitro antioxidant properties of six sponge species
collected from Kish Island in the Persian Gulf. We evaluated the effects of different concentrations of the dichloromethane and methanolic extracts of six sponges on scavenging DPPH and OH free radicals. The activities of these extracts were compared with those of commercial antioxidants such as gallic acid. The maximum level of DPPH radical scavenging (0.234± 0.033 mg/ml) was observed for the methanolic extract of Pseudosaberites clavatus in the reaction mixture. Also, most of sponge extracts exhibited medium to high hydroxyl radical scavenging activity. The results of this study suggest that marine sponges of the Persian Gulf are promising sources of antioxidants.
Keywords:
- Antioxidant activity
- Marine sponges
- Persian Gulf
- Reactive free radical.
How to Cite
Hassan Seradj, Mahmoodreza Moein, Masoumeh Eskandari, & Faramarz Maaref. (2012). Antioxidant Activity of Six Marine Sponges Collected from the Persian Gulf: Antioxidant activity of marine sponges. Iranian Journal of Pharmaceutical Sciences, 8(4), 249–255. https://doi.org/10.22037/ijps.v8.40926
References
[1] Bhakuni DS, Rawat DS. Bioactive marine natural products. 2005, Springer and Anamaya Publishers:New Delhi, India.
[2] Newbold RW, Jensen PR, Fenical W, Pawlik JR.Antimicrobial activity of Caribbean sponge extracts. Aquat MicrobEcol 1999; 19: 279-84.
[3] Faulkner DJ. Highlights of marine natural products chemistry (1972-1999). Nat Prod Rep 2000; 17: 1-6.
[4] Sipkema D, Franssen MCR, Osinga R, Tramper J, Wijffels RH. Marine sponges as Pharmacy.Mar Biotechnol 2005; 7: 142-62.
[5] Rangel M, Sanctis B, Freitas JC, Polatto JM, Granato AC, Berlinck RGS , Hadju E. Cytotoxic and neurotoxic activities in extracts of marine sponges from southeastern Brazilian coast. J Exp Biol Ecol 2001; 262: 31-40.
[6] Touati I, ChaiebK, Bakhrouf A, Gaddour K.Screening of antimicrobial activity of marine sponge extracts collected from Tunisian coast. J Med Mycol 2007; 17: 183-6.
[7] Ferreira M, Cabado AG, Chapela M, Fajardo P, Atanassova M, Garrido A, Vieites JM, Lago J.Cytotoxic activity of extracts of marine sponges from NW Spain on a neuroblastoma cell line Environ Toxicol Pharmacol 2011; 32: 430-7.
[8] Lakshmi V, Mishra SK, Srivastava S, Chaturvedi A, Srivastava MN, Shukla PK. Antifungal activity of marine sponge Haliclonaexigua (Krikpatrick).J Med Mycol 2010; 20: 31-3.
[9] Li H, Shigeki S, Fusetani N. Simple antifungal metabolites from a marine sponge, Halichondria sp. Comp Biochem Physiol Part B: Comp Biochem 1994; 107: 261-4.
[10] Chairman K, Ranjit Singh AJA, Alagumuthu G.Cytotoxic and antioxidant activity of selected marine sponges. Asian Pacific J Trop Disease 2012; 2: 234-8.
[11] Wickens PA. Aging and free radical theory. Respir Physiol 2001; 128: 379-91.
[12] Ozyurek M, Bektasoglu B, Guclu K, Apak R.Hydroxyl radical scavenging assay of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method using catalase for hydrogen peroxide degradation. Anal Chim Acta 2008; 616: 196-206.
[13] Halliwell H. Free radicals, antioxidants, and human disease: curiosity, cause or consequence.Lancet 1994; 344: 721.
[14] Safaeian S, Hosseini H, Farmohamadi S, Mohtarami A, Abbas Pour A. First record of marine sponges of Nay Band and Bandar Bustaneh, Persian Gulf, Iran. J Marine Sci 2007;????: 1-14.
[15] Safaeian S, Hosseini H, Abbas Pour Asadolah A, Farmohamadi S. Antimicrobial activity of marine sponge extracts of offshore zone from Nay Band Bay, Iran. J Mycol Med 2009; 19: 11-6.
[16] Prakasa Rao TS, Sarma NS, Murthy YLN, Kantamreddi V, Wright CW, Parameswaran PS.New polyhydroxy sterols from the marine sponge Callyspongiafibrosa (Ridley and Dendly). Tet Lett 2010; 51: 3583-6.
[17] Zhidkov ME, Baranova OV, Balaneva NN, Fedorov SN, Radchenko OS, Dubovitskii SV.The first syntheses of 3-bromofascaplysin, 10-bromofascaplysin and 3, 10-dibromofascaplysin marine alkaloids from Fascaplysinopsis reticulata and Didemnum sp. by application of a simple and effective approach to the pyrido[1,2-a:3,4-b]diindole system. Tet Lett 2007; 48: 7998-8000.
[18] Jiménez C, Quiñoá E, Crews P. Novel marine sponge alkaloids 3. β-carbolinium salts from Fascaplysinopsis reticulata. Tet Lett 1991; 32: 1843-6.
[19] Segraves NL, Lopez S, Johnson TA, Said SA, Xiong Fu , Schmitz FJ, Pietraszkiewicz H, Valeriote FA, Crews P. Structures and cytotoxicities of fascaplysin and related alkaloids from two marine Fascaplysinopsis sponge and Didemnum tunicate. Tet Lett 2003; 44: 3471-5.
[20] Mayer AM, Gustafson KR. Marine pharmacology in 2005-2006: antitumour and cytotoxic compounds. Eur J Cancer 2008; 44: 2357-87.
[21] Hermes-lima M, Wang EM, Schulman HM, Storey KB, Ponka P. Deoxyribose degradation catalyzed by Fe (III)-EDTA: kinetic aspects and potential usefulness for sub micromolar iron measurements. Mol Cell Biochem 1994; 137: 65-73.
[22] Chung S K, Osawa T, Kawakishi S. Hydroxyl radical scavenging effect of spices and scavengers from Brown Mustard. Biosci Biotech Biochem 1997; 61: 118-24.
[23] Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
[24] Brand-Williams W, Cuvelier ME, Berset, C. Use of free radical method to evaluate antioxidant activity. Lebensmittel-Wissenschaft and Technologie 1995; 28: 25-30.
[25] Manian R, Anusuya N, Siddhuraju P, Manian S.The antioxidant activity and free radical scavenging potential of two different solvent extracts of Camellia sinensis (L.) O. Kuntz, Ficusbengalensis L. and Ficusracemosa L. Food Chem 2008; 107: 1000-7.
[26] Hochestein P, Atallah AS. The nature of oxidant and antioxidant systems in the inhibition of mutation and cancer. Mutation Res 1988; 202:363-75.
[27] Mannix D, Langridge S, Lander GH, Rebizant J, Longfield MJ, Stirling WGl. Experiments on transuranium compoundswith x-ray resonant exchange scattering. Physica B: Physica Condensed Matter 1999; 262: 125-40.
[28] Soares JR, Dinis TP, Cunha AP, Ameida LM.Antioxidant activity of some extracts of Thymus zygis. Free Radical Res 1997; 26: 469-78.
[29] Baumann J, Wurn G, Bruchlausen FV. 1979.Prostaglandin synthetase inhibiting O-2 radical scavenging properties of some flavonoids and related phenolic compounds. Naunyn-Schmiedebergs Arch Pharmacol 1979; R27: 308.
[2] Newbold RW, Jensen PR, Fenical W, Pawlik JR.Antimicrobial activity of Caribbean sponge extracts. Aquat MicrobEcol 1999; 19: 279-84.
[3] Faulkner DJ. Highlights of marine natural products chemistry (1972-1999). Nat Prod Rep 2000; 17: 1-6.
[4] Sipkema D, Franssen MCR, Osinga R, Tramper J, Wijffels RH. Marine sponges as Pharmacy.Mar Biotechnol 2005; 7: 142-62.
[5] Rangel M, Sanctis B, Freitas JC, Polatto JM, Granato AC, Berlinck RGS , Hadju E. Cytotoxic and neurotoxic activities in extracts of marine sponges from southeastern Brazilian coast. J Exp Biol Ecol 2001; 262: 31-40.
[6] Touati I, ChaiebK, Bakhrouf A, Gaddour K.Screening of antimicrobial activity of marine sponge extracts collected from Tunisian coast. J Med Mycol 2007; 17: 183-6.
[7] Ferreira M, Cabado AG, Chapela M, Fajardo P, Atanassova M, Garrido A, Vieites JM, Lago J.Cytotoxic activity of extracts of marine sponges from NW Spain on a neuroblastoma cell line Environ Toxicol Pharmacol 2011; 32: 430-7.
[8] Lakshmi V, Mishra SK, Srivastava S, Chaturvedi A, Srivastava MN, Shukla PK. Antifungal activity of marine sponge Haliclonaexigua (Krikpatrick).J Med Mycol 2010; 20: 31-3.
[9] Li H, Shigeki S, Fusetani N. Simple antifungal metabolites from a marine sponge, Halichondria sp. Comp Biochem Physiol Part B: Comp Biochem 1994; 107: 261-4.
[10] Chairman K, Ranjit Singh AJA, Alagumuthu G.Cytotoxic and antioxidant activity of selected marine sponges. Asian Pacific J Trop Disease 2012; 2: 234-8.
[11] Wickens PA. Aging and free radical theory. Respir Physiol 2001; 128: 379-91.
[12] Ozyurek M, Bektasoglu B, Guclu K, Apak R.Hydroxyl radical scavenging assay of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method using catalase for hydrogen peroxide degradation. Anal Chim Acta 2008; 616: 196-206.
[13] Halliwell H. Free radicals, antioxidants, and human disease: curiosity, cause or consequence.Lancet 1994; 344: 721.
[14] Safaeian S, Hosseini H, Farmohamadi S, Mohtarami A, Abbas Pour A. First record of marine sponges of Nay Band and Bandar Bustaneh, Persian Gulf, Iran. J Marine Sci 2007;????: 1-14.
[15] Safaeian S, Hosseini H, Abbas Pour Asadolah A, Farmohamadi S. Antimicrobial activity of marine sponge extracts of offshore zone from Nay Band Bay, Iran. J Mycol Med 2009; 19: 11-6.
[16] Prakasa Rao TS, Sarma NS, Murthy YLN, Kantamreddi V, Wright CW, Parameswaran PS.New polyhydroxy sterols from the marine sponge Callyspongiafibrosa (Ridley and Dendly). Tet Lett 2010; 51: 3583-6.
[17] Zhidkov ME, Baranova OV, Balaneva NN, Fedorov SN, Radchenko OS, Dubovitskii SV.The first syntheses of 3-bromofascaplysin, 10-bromofascaplysin and 3, 10-dibromofascaplysin marine alkaloids from Fascaplysinopsis reticulata and Didemnum sp. by application of a simple and effective approach to the pyrido[1,2-a:3,4-b]diindole system. Tet Lett 2007; 48: 7998-8000.
[18] Jiménez C, Quiñoá E, Crews P. Novel marine sponge alkaloids 3. β-carbolinium salts from Fascaplysinopsis reticulata. Tet Lett 1991; 32: 1843-6.
[19] Segraves NL, Lopez S, Johnson TA, Said SA, Xiong Fu , Schmitz FJ, Pietraszkiewicz H, Valeriote FA, Crews P. Structures and cytotoxicities of fascaplysin and related alkaloids from two marine Fascaplysinopsis sponge and Didemnum tunicate. Tet Lett 2003; 44: 3471-5.
[20] Mayer AM, Gustafson KR. Marine pharmacology in 2005-2006: antitumour and cytotoxic compounds. Eur J Cancer 2008; 44: 2357-87.
[21] Hermes-lima M, Wang EM, Schulman HM, Storey KB, Ponka P. Deoxyribose degradation catalyzed by Fe (III)-EDTA: kinetic aspects and potential usefulness for sub micromolar iron measurements. Mol Cell Biochem 1994; 137: 65-73.
[22] Chung S K, Osawa T, Kawakishi S. Hydroxyl radical scavenging effect of spices and scavengers from Brown Mustard. Biosci Biotech Biochem 1997; 61: 118-24.
[23] Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
[24] Brand-Williams W, Cuvelier ME, Berset, C. Use of free radical method to evaluate antioxidant activity. Lebensmittel-Wissenschaft and Technologie 1995; 28: 25-30.
[25] Manian R, Anusuya N, Siddhuraju P, Manian S.The antioxidant activity and free radical scavenging potential of two different solvent extracts of Camellia sinensis (L.) O. Kuntz, Ficusbengalensis L. and Ficusracemosa L. Food Chem 2008; 107: 1000-7.
[26] Hochestein P, Atallah AS. The nature of oxidant and antioxidant systems in the inhibition of mutation and cancer. Mutation Res 1988; 202:363-75.
[27] Mannix D, Langridge S, Lander GH, Rebizant J, Longfield MJ, Stirling WGl. Experiments on transuranium compoundswith x-ray resonant exchange scattering. Physica B: Physica Condensed Matter 1999; 262: 125-40.
[28] Soares JR, Dinis TP, Cunha AP, Ameida LM.Antioxidant activity of some extracts of Thymus zygis. Free Radical Res 1997; 26: 469-78.
[29] Baumann J, Wurn G, Bruchlausen FV. 1979.Prostaglandin synthetase inhibiting O-2 radical scavenging properties of some flavonoids and related phenolic compounds. Naunyn-Schmiedebergs Arch Pharmacol 1979; R27: 308.
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