Pharmacognostic and Preliminary Phytochemical Investigation on Doronicum scorpioides Roots Pharmacognosy and phytochemistry of Doronicum scorpioides
Iranian Journal of Pharmaceutical Sciences,
卷 8 编号 4 (2012),
1 مهر 2012
,
第 257-262 页
https://doi.org/10.22037/ijps.v8.40927
摘要
In many herbal markets medicinal plants are sold in dried forms which make it difficult to authenticate them and recognize the adulterations. In the present study the preliminary pharmacognostic parameters including microscopieal studies, extractive values and thin layer chromatography analysis of roots of Doronicum scorpioides (Asteraceae) were evaluated. Three fractions of the plant (hexane,
dichloromethane and ethanolic) were applied to the silica gel plates and run in nonpolar, semi polar and polar mobile phases. Chromatographic spots were visualized using different spray reagents. The preliminary screening of the D. scorpioides roots revealed the constituents of the different fractions of the roots including alkaloids, flavonoids, triterpenes saponins, coumarins and essential oils which can be a useful guide for further phytochemical and pharmacognostic research. This is the first report on phytochemical constituents of D. scorpioides roots. Also the pharmacognostic investigation of the D. scorpioides root can be a reliable method for authentication of the medicinal part of the plant and to recognize any adulterations.
- Doronicum scorpioides
- Microscopic studies
- Pharmacognostic investigation
- Quality Control.
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参考
[2] Liang YZ, Xie P, Chan K. Quality control of herbal medicines. J Chromatogr B 2004; 812:53-70.
[3] Indhumathi D, Kalvimoorthi. Pharmacognostic preliminary phytochemical and antimicrobial activity on the whole plant of Sarcostemma secomone (L) bennet. Int J Pharm Sci Rev Res 2010; 1: 49-55.
[4] Galand N, Pothier J, Viel C. Plant drug analysis by planar chromatography. J Chromatogr Sci 2002; 40: 585-97.
[5] Ganzera M. Quality control of herbal medicines by capillary electrophoresis: potential, requirements and applications. Electrophoresis 2008; 29: 3489-503.
[6] Calixto JB. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res 2000; 33: 179-89.
[7] Lev E. Reconstructed materia medica of the Medieval and Ottoman al-Sham. J Ethnopharmacol 2002; 80: 167-79.
[8] Aghili MH. Makhzan-al-Advia [electronic book]. Edited by Rahimi R, Shams Ardekani MR, Farjadmand F. Tehran: Tehran University of Medical Sciences, 2009; pp. 385-6. Available from: http://aqlibrary.org/UserFiles/File/makhzan.pdf.
[9] Upton R, Graff A, Jolliffe G, Länger R, Williamson E. American herbal pharmacopoeia: botanical pharmacognosy, microscopic characterization of botanical medicines. New York: CRC Press, 2011; pp. 66-8.
[10] Jackson BP, Snowdon DW. Atlas of microscopy of medicinal plants, culinary herbs, and spices. London: CRC Press, 1990; pp. 6-11.
[11] Pascual ME, Carretero ME, Slowing KV, Villar A. Simplified screening by TLC of plant drugs. Pharm Biol 2002; 139-43.
[12] Jhade D, Ahirwar D, Jain R, Sharma N, Gupta S.Pharmacognostic standardization, physico- and phytochemical evaluation of Amaranthus spinosus linn. Root. J Young Pharm 2011; 3: 221-5.
[13] Bohlmann F, Abraham W. Ein neuer sesquiterpenalkohol und andere inhaltsstoffe aus Doronicum pardalianches. Phytochemistry 1979; 18: 668-71.
[14] Paolini J, Muselli A, Bernardini A, Bighelli A, Casanova J, Costa J. Thymol derivatives from essential oil of Doronicum corsicum L. Flavour Frag J 2007; 22: 479-87.
[15] Lazarević J, Radulović N, Palić R, Zlatkovic B.Chemical composition of the essential oil of Doronicum austriacum Jacq. subsp. giganteum (Griseb.) Stoj. et Stef. (Compositae) From Serbia.J Essent Oil Res 2009; 21: 507-10.
[16] Mohsin M, Khan AB, Hakim MH, Latafat T.Therapeutic evaluation of Qalbeen- A polyherbal mineral formulation in ischaemic heart disease. Indian J Trad Know 2008; 7: 575-80.
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